PrivEsc LPE Question - Privilege escalation

[chaos_exe]

Hi. I get local users with joined to domain more often. I have a question about becoming a local admin. How difficult is it to exploit local users on a domain-joined machine compared to a workgroup machine? Additionally, how much harder is it to exploit workstations compared to servers? Finally, what is the likelihood of gaining local administrator privileges with or without antivirus software? Any answer is appreciated